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Updates on Age to Start and Stop Colorectal Cancer Screening: Recommendations From the U.S. Multi-Society Task Force on Colorectal Cancer.

Department of Internal Medicine, Division of Gastroenterology, University of Colorado Anschutz Medical Center, Aurora, Colorado, USA. Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, Colorado, USA. Department of Internal Medicine, Division of Gastroenterology, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA. Vatche and Tamar Manoukian Division of Digestive Diseases and Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, California, USA. Department of Internal Medicine, Division of Gastroenterology, Veterans Affairs Medical Center, White River Junction Vermont and the Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA. University of Connecticut School of Medicine, Farmington, Connecticut, USA. Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic, Cleveland, Ohio, USA. National Gastroenterology and Hepatology Program, Veterans Health Administration and the Department of Medicine, Division of Gastroenterology, University of Washington School of Medicine, Seattle, Washington, USA. Department of Internal Medicine, Division of Gastroenterology, New York University Langone Health, New York, New York, USA. Department of Internal Medicine, Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts, USA. Department of Internal Medicine, Division of Gastroenterology, Minneapolis Veterans Affairs Medical Center and University of Minnesota, Minneapolis, Minnesota, USA.

The American journal of gastroenterology. 2022;(1):57-69
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Abstract

This document is a focused update to the 2017 colorectal cancer (CRC) screening recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer, which represents the American College of Gastroenterology, the American Gastroenterological Association, and the American Society for Gastrointestinal Endoscopy. This update is restricted to addressing the age to start and stop CRC screening in average-risk individuals and the recommended screening modalities. Although there is no literature demonstrating that CRC screening in individuals under age 50 improves health outcomes such as CRC incidence or CRC-related mortality, sufficient data support the U.S. Multi-Society Task Force to suggest average-risk CRC screening begin at age 45. This recommendation is based on the increasing disease burden among individuals under age 50, emerging data that the prevalence of advanced colorectal neoplasia in individuals ages 45 to 49 approaches rates in individuals 50 to 59, and modeling studies that demonstrate the benefits of screening outweigh the potential harms and costs. For individuals ages 76 to 85, the decision to start or continue screening should be individualized and based on prior screening history, life expectancy, CRC risk, and personal preference. Screening is not recommended after age 85.

Methodological quality

Publication Type : Meta-Analysis

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